Esters of dehydroepiandrosterone (DHEA) as probes for the active site of type 3 17β-hydroxysteroid dehydrogenase (17β-HSD3)
We report the use of steroid-based compounds as probes for the active site of 17β-hydroxysteroid dehydrogenase, in particular, type 3 (17β-HSD3). Results suggest that the compounds were good inhibitors of 17β-HSD3 - a number were extremely potent with respect to the standard compounds used.
