- 3,3'-SPIROINDOLINONE DERIVATIVES AND THEIR USE FOR CANCER
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There are provided compounds of the formula (I) or a pharmaceutically acceptable salt or ester thereof wherein X, Y, W, W?,V, V?, V", R1, R2 and R3 are as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer
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Page/Page column 42-43
(2010/11/05)
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- Spiroindolinone Derivatives
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There are provided compounds of the formula and pharmaceutically acceptable salts and esters and enantiomers thereof wherein W, X, X′, Y, V, V′, A, B and R are as described herein. The compounds have utility as antiproliferative agents, especially, as anticancer agents.
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Page/Page column 26
(2009/07/10)
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- ORGANIC COMPOUNDS
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A compound of formula (I); in free or pharmaceutically acceptable salt form, where R1, R2, R3, R4, R5, m, n, w, X, Y and Q have the meanings as indicated in the specification, are useful for treating conditions mediated by the CRTh2 receptor, especially inflammatory or obstructive airways diseases.
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Page/Page column 27-28
(2008/06/13)
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