25406-56-8

Four new triterpenoid saponins named kalopanax-saponins C (4), D (5), E (6) and F (7) were isolated from the roots of Kalopanax septemlobus (THUNB.) KOIDZ. together with three known saponins, kalopanax-saponins A (1) and B (2), and chikusetsusaponin IV (3).On the basis of chemical and spectral data, the structures of these new saponins were elucidated to be as follows: (4), 3-O-α-rhamnopyranosyl-(1->2)-3)>-α-arabinopyranosyl hederagenin 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (5), 3-O-α-rhamnopyranosyl-(1->2)-3)>-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (6), 3-O-β-glucopyranosyl-(1->3)-β-glucuronopyranosyl oleanolic acid; (7), 3-O-α-arabinopyranosyl-(1->2)-3)>-β-glucuronopyranosyl oleanolic acid 28-O-β-glucopyranosyl ester.Keywords - Kalopanax septemlobus; Araliaceae; saponin; kalopanax-saponin; oleanolic acid glycoside; hederagenin glycoside; Chinese folk medicine; ciqiu

-