- New compound Malabemide, preparation method and uses thereof
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The invention discloses a new compound Malabemide with a molecule formula represented by a formula h, a preparation method and pharmaceutical applications thereof, wherein ethanolamine and 5-chloro-2-pyridinecarboxylic acid are used as starting raw materials, corresponding intermediates 2-bromoethylamine hydrobromide and 5-chloro-2-pyridinecarbonyl chloride are respectively synthesized, and are subjected to a reaction to generate 5-chloro-N-(2-bromoethyl)-2-pyridinecarboxamide, and the 5-chloro-N-(2-bromoethyl)-2-pyridinecarboxamide and morpholine are subjected to condensation to generate Malabemide h. According to the present invention, the preparation method has characteristics of easily available raw materials, simple operation, good product purity and high yield, and is suitable for industrial production. The formula h is defined in the specification.
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Paragraph 0024; 0025-0026
(2018/11/03)
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- Modifying silica with viologenic groups
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Modification of silica with viologenic groups is described. N,N'-Diallyl-γ,γ-dipyridinium dibromide obtained by the reaction of allyl bromide with γ,γ-dipyridyl was hydrosilylated with triethoxysilane followed by copolycondensation of the synthesized bis(3-triethoxysilylpropyl)-γ,γ'-dipyridinium dibromide with tetraethoxysilane. Pleiades Publishing, Ltd., 2010.
- Dzaraeva,Arutyuniantz,Archegova,Shpakov
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scheme or table
p. 1029 - 1033
(2011/01/06)
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