- Study of the acylation reaction of 2,6-dimethyl-3,5-pyridinedicarboxylic acid hydrazides
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Acylation of 3-ethoxycarbonyl-2,6-dimethyl-5-pyridinecarboxylic acid hydrazide and 2,6-dimethyl-3,5-pyridinedicarboxylic acid dihydrazide using aromatic acid chlorides gave the corresponding N-aroyl hydrazides. It was found that the hydrazinolysis of 3-ethoxycarbonyl-2,6-dimethyl-5-pyridine-dicarboxylic acid N-aroyl hydrazides occurred not at the ester group but as a rehydrazinolysis reaction at the dihydrazide fragment. 2005 Springer Science+Business Media, Inc.
- Nesterova,Voevudsky,Samukha,Zubatyuk,Shishkin
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- A peptidomimetic-based thixotropic organogel showing syneresis-induced anti-adhesion against water and ice
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The self-assembly, organogelation, syneresis, and anti-adhesion properties of a peptidomimetic containing l-phenylalanine and 2,6-dimethylpyridine 3,5-dicarboxylic acid have been studied in detail. The peptidomimetic forms a transparent gel in aromatic solvents such as benzene, toluene, xylene and chlorobenzene. The hierarchical nature of the self-assembly process in the gel was characterized by a combination of POM and FE-SEM imaging, revealing an entangled fiber network. The rheology measurements then confirmed the formation of a thixotropic organogel. The storage modulus was about one order of magnitude higher than the loss modulus, which indicates the physical crosslinking in the organogel. The gel exhibits significant self-healing properties and allows diffusion of rhodamine 6G through the gel matrix. The peptidomimetic gel shows syneresis under an appropriate environment. The peptidomimetic organogel surfaces exhibit syneresis-induced anti-adhesion properties against ice and water. This peptidomimetic gelator molecule, being economically viable and easy to synthesize, has great prospects in materials chemistry.
- Gumtya, Milan,Haldar, Debasish,Ibukun, Olamilekan Joseph,Kumar, Santosh,Mondal, Sahabaj
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p. 1105 - 1110
(2022/02/07)
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