- Low-Temperature Intramolecular [4+2] Cycloaddition of Allenes with Arenes for the Synthesis of Diene Ligands
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The intramolecular [4+2] cycloaddition between arenes and allenes first reported by Himbert gives rapid access to rigid polycyclic scaffolds. Herein, we report a one-pot oxyalkynylation/cycloaddition reaction proceeding under mild conditions (23–90 °C) an
- Hari, Durga Prasad,Pisella, Guillaume,Wodrich, Matthew D.,Tsymbal, Artem V.,Tirani, Farzaneh Fadaei,Scopelliti, Rosario,Waser, Jerome
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supporting information
p. 5475 - 5481
(2021/01/21)
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- Three-Component Reaction for the Synthesis of Highly Functionalized Propargyl Ethers
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Multicomponent reactions provide efficient means to access molecular complexity. Herein, we report a copper-catalyzed three-component reaction of diazo compounds, alcohols and ethynyl benziodoxole (EBX) reagents for the synthesis of propargyl ethers. Extensive variations of the three partners of the reaction is possible, leading to highly functionalized and structurally diverse products under mild conditions. Alkynylation of a copper ylide intermediate is postulated as key step for this transformation.
- Pisella, Guillaume,Gagnebin, Alec,Waser, Jér?me
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supporting information
p. 10199 - 10204
(2020/07/17)
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- Chemistry of diazopolycarbonyl compounds: V. Synthesis, structure, and chemical characteristics of aryl diazoacetates
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Aryl diazoacetates were prepared, and basing on spectral data and quantum-chemical calculations cis-trans isomerism thereof was proved. The reactions of diazoesters with hydrochloric and sulfuric acids, triphenylphosphine, and dinitrogen tetroxide resulted respectively in aryl chloroacetates, bis(aryloxy-carbonylmethyl) sulfates, triphenylphosphoranylidenehydrazones of aryl 2-oxoethanoates, and N-oxides of diaryl 1,2,5-oxadiazole-3,4-dicarboxylates.
- Zalesov,Kataev
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p. 1666 - 1672
(2007/10/03)
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