Microwave-assisted synthesis of 1,3-benzodioxole derivatives from catechol and ketones or aldehydes
An efficient synthetic procedure for the preparation of a diverse library of 1,3-benzodioxoles was developed by applying controlled microwave heating in comparison with currently available conventional heating. Reactions were completed in less than 3 h. The isolation of product is simple, the isolated yields are good to excellent, and this method is applicable to large scale production.
Pingali, Subramanya R.K.,Jursic, Branko S.
experimental part
p. 4371 - 4374
(2011/09/19)
An efficient and convenient method for preparation of 2,2-disubstituted and 2-monosubstituted 1,3-benzodioxoles from ketones and aldehydes with catechol catalysed by zro2/so42-
The title compounds have been synthesised by reaction of catechol with ketones and aldehydes catalysed by ZrO2/SO42- solid superacid in high yields. Ketones gave better yields than aldehydes.
Jin,Zhang,Wang,Guo,Li
p. 289 - 291
(2007/10/03)
Montmorillonite clay catalysis. Part 14. A facile synthesis of 2-substituted and 2,2-disubstituted 1,3-benzodioxoles
A series of 2-substituted and 2,2-disubstituted 1,3-benzodioxoles have been synthesised by reaction of catechol and pyrogallol with corresponding aldehydes and ketones catalysed by montmorillonite KSF or K-10. The reactions are completed within 2.7-24 h to give satisfactory yields. Ketones give better yields than aldehydes, although highly sterically hindered ketones and diaryl ketones fail to react at all.
Li, Tong-Shuang,Li, Li-Jun,Lu, Bo,Yang, Feng
p. 3561 - 3564
(2007/10/03)
Synthesis of 2- and 2,2-Substituted 4,5-Benzo-1,3-dioxolanes
Pyrocatechol reacts with carbonyl compounds in the presence of phosphorus trichloride to give corresponding 2- and 2,2-substituted 4,5-benzo-1,3-dioxolanes in high yields.
An Improved Method for the Synthesis of 2,2-disubstituted and 2-Monosubstituted 1,3-Benzodioxoles
The reactions of catechol with ketones and aldehydes have been studied and convenient procedures have been developed for the preparation of the title compounds in high yields.These products undergo virtually quantitative nitration at position 5, thus providing a source of derivatives substituted in the benzene ring.
Cole, Edward R.,Crank, George,Minh, H. T. Hai
p. 675 - 680
(2007/10/02)
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