Generation of o-quinodimethanes (o-QDMs) from benzo[c]oxepines and the synthetic application for polysubstituted tetrahydronaphthalenes
A novel method for the generation of o-quinodimethane (o-QDM) intermediates is reported using a mild and efficient base-promoted ring-opening of benzo[c]oxepines. Among the benzo[c]oxepines studied, indanone containing analogues demonstrated the greatest