Conversion of Thiochroman-4-one into the corresponding Spiro-thiazole and -pyrimidine Derivatives
Reaction of cysteine and 2-aminothiophenol with thiochroman-4-one gives thiazoline and benzothiazoline derivatives 1 and 2, respectively.Thiochroman-4-one with bromide and thiourea forms 2-aminothiazole derivative (3).Thiochroman-4-one with urea and thiourea in the presence of benzaldehyde gives pyrimidine derivatives 4 and 5, respectively.
Joshi, B. C.,Gogia, Santosh,Kishore, Dharma
p. 280 - 281
(2007/10/02)
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