- “On water” ultrasound-assisted one pot efficient synthesis of functionalized 2-oxo-benzo[1,4]oxazines: First application to the synthesis of anticancer indole alkaloid, Cephalandole A
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For the first time, an efficient, simple, synthetic green protocol for the one-pot synthesis of functionalized 2-oxo-benzo[1,4]oxazines 24–29 in water under ultrasound irradiation is presented. As compared to conventional methods, the present protocol avo
- Jaiswal, Pradeep K.,Sharma, Vashundhra,Prikhodko, Jaroslav,Mashevskaya, Irina V.,Chaudhary, Sandeep
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- Non-peptide-based new class of platelet aggregation inhibitors: Design, synthesis, bioevaluation, SAR, and in silico studies
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A series of 2-oxo-2-phenylethylidene linked 2-oxo-benzo[1,4]oxazine analogues 17a–x and 18a–o, incorporated with a variety of electron-withdrawing as well as electron-donating groups at ring A and ring C, were synthesized under greener conditions in excel
- Jaiswal, Pradeep K.,Sharma, Vashundhra,Kumar, Surendra,Mathur, Manas,Swami, Ajit K.,Yadav, Dharmendra K.,Chaudhary, Sandeep
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- Five-membered 2,3-dioxo heterocycles: XCVIII.* [4 + 2]-cycloaddition of alkyl vinyl ethers to 3-aroyl-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4- triones. A new synthetic approach to heteroanalogs of 13(14→8)-abeo steroids
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3-Aroyl-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones reacted with alkyl vinyl ethers according to the [4 + 2]-cycloaddition pattern with formation of substituted (1S*,16R*)- and (1R*,16R*)-16-alkoxy-14- aryl-3,15-dioxa-10-azatetracyclo[8.7.0.01,13.04,9
- Stepanova,Aliev,Maslivets
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p. 1762 - 1767
(2014/08/05)
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- Five-membered 2,3-dioxo heterocycles: LXXVII. [4 + 2]-cycloaddition of alkyl vinyl ethers to 3-aroylpyrrolo[2,1-c][1,4]benzoxazine-1,2,4(4H)-triones
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[4 + 2]-Cycloaddition of 3-aroylpyrrolo[2,1-c][1,4]benzoxazine-1,2,4(4H)- triones to alkyl vinyl ethers gave substituted stereoisomeric (1R,16R)- and (1S,16R*)-16-alkoxy-14-aryl-3,15-dioxa-10-azatetracyclo[ 8.7.0.0 1,13.04,9]heptadec
- Stepanova,Babenysheva,Maslivets
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experimental part
p. 937 - 940
(2011/10/09)
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- Chemistry of acyl(imidoyl)ketenes: IX. Synthesis and thermolysis of 3-aroyl-8-chloro-1,2-dihydro-4H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones
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Reactions of 3-Z-aroylmethylene-6-chloro-3,4-dihydro-2H-1,4-benzoxazine-2- ones with oxalyl chloride afford 3-aroyl-8-chloro-1,2-dihydro-4H-pyrrolo[2,1-c] [1,4]benzoxazine-1,2,4-triones and Z-3-(2-aryl-2-chlorovinyl)-6-chloro-2H-1,4- benzoxazine-2-ones. A
- Semenova,Krasnykh
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p. 1222 - 1227
(2007/10/03)
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