Oligonucleotide analogues with a nucleobase-including backbone. Part 5: 2′-deoxy-8-(hydroxymethyl)adenosine- and 2′-deoxy-6-(hydroxymethyl)uridine-derived phosphoramidites: Synthesis and incorporation into 14-mer DNA strands
The pairing propensity of new DNA analogues with a phosphinato group between O-C(3′) and a newly introduced OCH2 group at C(8) and C(6) of 2′-deoxyadenosine and 2′-deoxyuridine, respectively, was evaluated by force-field calculations and Maruze
Czechtizky, Werngard,Vasella, Andrea
p. 594 - 612
(2007/10/03)
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