- Cobalt-bridged secondary building units in a titanium metal-organic framework catalyze cascade reduction of N-heteroarenes
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We report here a novel Ti3-BPDC metal-organic framework (MOF) constructed from biphenyl-4,4′-dicarboxylate (BPDC) linkers and Ti3(OH)2 secondary building units (SBUs) with permanent porosity and large 1D channels. Ti-OH groups from neighboring SBUs point toward each other with an O-O distance of 2 ?, and upon deprotonation, act as the first bidentate SBU-based ligands to support CoII-hydride species for effective cascade reduction of N-heteroarenes (such as pyridines and quinolines) via sequential dearomative hydroboration and hydrogenation, affording piperidine and 1,2,3,4-tetrahydroquinoline derivatives with excellent activity (turnover number ~ 1980) and chemoselectivity.
- Feng, Xuanyu,Song, Yang,Chen, Justin S.,Li, Zhe,Chen, Emily Y.,Kaufmann, Michael,Wang, Cheng,Lin, Wenbin
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p. 2193 - 2198
(2019/02/20)
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- Gas-phase Pyrolysis of 2,3-Dihydro-1,4-diazepines: Involvement of the Saturated Portion of the Ring in Chemical Reactions and Novel cis-trans Isomerisation of a Fused Ring System
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Flash vacuum pyrolysis of 2,3-dihydro-1,4-diazepines in the range 450-550 deg C involves interaction of the saturated portion of the molecule with the vinamidine system and causes 1,5-hydrogen shifts which have been established by deuterium labelling experiments; at higher temperatures, ring contraction occurs to give pyrazines as major products.
- Ellis, Michael J.,Lloyd, Douglas,McNab, Hamish,Walker, Marion J.
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p. 2337 - 2338
(2007/10/02)
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