- Expedient synthesis of N[sbnd]Oxy-Heterocyclic Carbenes (NOHC) ligands and metal complexes using mechanochemistry
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1,3-Di(benzyloxy)imidazol-2-ylidenes (or NOHCs) possess structures related to N-heterocyclic carbenes (NHCs), with potentially useful applications including the stabilization of metals. In order to prepare NOHC metal complexes, a multi-step synthesis invo
- Bantreil, Xavier,Lamaty, Frédéric,Lauriol, Ga?tan,Mlostoń, Grzegorz,Wróblewska, Aneta
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supporting information
(2021/07/10)
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- Thermal rearrangement of an N-hydroxyimidazole thiocarbamoyl derivative as a simple entry into the 4-thioimidazole motif
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A thermal rearrangement of a thio-ester derivative of N-hydroxyimidazole gives rise, in a clean reaction, to the corresponding 4-and 2-thiol ester derivatives in a 1 : 1 ratio.
- Pinto, Luis F. V.,Justino, Goncalo C.,Vieira, Abel J. S. C.,Prabhakar, Sundaresan,Lobo, Ana M.
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scheme or table
p. 17 - 23
(2010/08/22)
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- Hydroxy-1H-imidazole-3-oxides - Synthesis, kinetic acidity, and application in catalysis and supramolecular anion recognition
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Using ab initio calculations (B3LYP 6-31G*) the geometries of diethyl, dimethoxy and dimethylamino imidazolium salts were studied as representative models of imidazolium salts bearing heteroatoms directly attached to the ring nitrogen atoms of
- Bartza, Susan,Blumenr?dera, Bettina,Kernb, Anika,Fleckensteinb, Julia,Frohnapfelb, Sabine,Schatz, Jürgen,Wagnerb, Alexander
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experimental part
p. 629 - 638
(2009/12/26)
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- NOVEL TYROSINASE INHIBITORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN HUMAN MEDICINE AND IN COSMETICS
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The present invention relates to the use of compounds corresponding to the following general formula (I) in pharmaceutical compositions intended for use in human or veterinary medicine or else in cosmetic compositions, and also to novel compounds of formula (II) and to the compositions comprising them.
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Page/Page column 19
(2008/06/13)
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- Synthesis of 2-Substituted 1-Hydroxyhnidazoles through Directed Lithiation
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Benzylation of 3-hydroxyimidazole 1-oxide gave 3-(benzyloxy)imidazole 1-oxide, which was deoxygenated with phosphorous trichloride to produce 1-(benzyloxy)imidazole. 1-(Benzyloxy)imidazole was deprotonated selectively at C-2 by n-butyllithium. The anion formed was reacted with electrophiles to give 1-(benzyloxy)imidazoles with carbon, halogen, silicon, or sulfur substituents at the 2-position. Subsequent debenzylation afforded 2-substituted 1-hydroxyimidazoles which in turn could be deoxygenated to give 2-substituted imidazoles.
- Eriksen, Birgitte Langer,Veds?, Per,Morel, Sandrine,Begtrup, Mikael
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- Preparation of N-Hydroxyazoles by Oxidation of Azoles
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Azoles without N-substituents are oxidized with per-acids or perborate to the corresponding N-hydroxy substituted azoles. 1,2,4-Triazole and tetrazole produce two isomers separated through their O-benzyl derivatives.Imidazole and 1,2,3- and 1,2,4-triazole can be di-oxygenated in low yields.N-Hydroxypyrazole is deoxygenated by per-acid.
- Begtrup, Mikael,Vedso, Per
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p. 243 - 248
(2007/10/02)
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- 1-Hydroxyimidazole Derivatives III. Synthesis of 1-Alkyloxy-, 1-Arylalkyloxy-, and 1-Phenoxy-1H-imidazoles
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1-Hydroxy-1H-imidazole and 2-alkyl-1-hydroxy-1H-imidazoles are prepared by selective hydrogenation of the corresponding 1-hydroxy-1H-imidazole 3-oxides and subsequently transformed to the 1-alkoxy, 1-arylalkyloxy and 1-phenoxy derivatives.
- Laus, Gerhard,Stadlwieser, Josef,Kloetzer, Wilhelm
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p. 773 - 775
(2007/10/02)
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