SAR and mode of action of novel non-nucleoside inhibitors of hepatitis C NS5b RNA polymerase
Novel non-nucleoside inhibitors of the HCV RNA polymerase (NS5b) with sub-micromolar biochemical potency have been identified which are selective for the inhibition of HCV NS5b over other polymerases. The structures of the complexes formed between several
Powers, Jay P.,Piper, Derek E.,Li, Yang,Mayorga, Veronica,Anzola, John,Chen, James M.,Jaen, Juan C.,Lee, Gary,Liu, Jinqian,Peterson, M. Greg,Tonn, George R.,Ye, Qiuping,Walker, Nigel P. C.,Wang, Zhulun
p. 1034 - 1046
(2007/10/03)
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