cas 35693-91-5, (2S)-2-(Methoxycarbonylamino)-4-(4,6-dimethyl-9-oxo-4,9-dihydro-1H-imidazo[1,2-a]purine-7-yl)butyric acid methyl ester

Articles about 35693-91-5Total 6 be found

Synthesis of β-hydroxywybutines, the most probable alternatives for the hypermodified base of rat liver phenylalanine transfer ribonucleic acid
Deoxygenation of the 1,2-glycol (±)-5 was achieved at the position adjacent to the heterocycle through the cyclic carbonate (±)-14, providing the monohydroxy compound 6. This new method of regioselective deoxygenation was employed for the first synthesis
Itaya, Taisuke,Watanabe, Nobuhide,Iida, Takehiko,Kanai, Tae,Mizutani, Akemi
p. 6419 - 6430
(2007/10/02)

Synthesis of 3-β-D-Ribofuranosylwybutine, the Most Probable Structure for the Hypermodified Nucleoside Isolated from Yeast Phenylalanine Transfer Ribonucleic Acids
An alternative synthesis of the key intermediate 8 for the synthesis of wybutine 1 has been attained through the Heck reaction between (S)-N-(methoxycarbonyl)vinylglycine 13 and 1-benzyl-7-iodowye 7.The nucleoside version of this method using 7-iodo-3-(2,
Itaya, Taisuke,Morisue, Masatoshi,Shimomichi, Manabu,Ozasa, Masako,Shimizu, Shigeyuki,Nakagawa, Satoshi
p. 2759 - 2766
(2007/10/02)

Synthesis and absolute configuration of wybutine, the fluorescent minor base from phenylalanine transfer ribonucleic acids
The phosphonium chloride 6 having an optically active amino acid moiety was synthesized from (S)-serine benzyl ester tosylate (2b) through a six-step route. The utility of 6 as a reagent for the Wittig reaction was exemplified in the olefination with benz
Itaya,Mizutani,Iida
p. 1407 - 1414
(2007/10/02)

ACCESS TO THE SYNTHESIS OF WYBUTOSINE, THE FIRST TRICYCLIC FLUORESCENT NUCLEOSIDE ISOLATED FROM PHENYLALANINE TRANSFER RIBONUCLEIC ACIDS
An improved synthesis of the key intermediate 5 for the chiral syntheses of wybutine (1c) and hydroxywybutine (1d) has been achieved by palladium-catalyzed vinylation, which has been utilized for the first synthesis of 3-β-D-ribofuranosylwybutine (2c).
Itaya, Taisuke,Shimomichi, Manabu,Ozasa, Masako
p. 4129 - 4132
(2007/10/02)

SYNTHESIS OF OPTICALLY ACTIVE FORMS OF HYDROXY-Y BASE, THE MINOR COMPONENT OF RAT LIVER PHENYLALANINE TRANSFER RIBONUCLEIC ACID
-β-Hydroxywybutine (6) and its -isomer (9) have been synthesized as the most probable alternatives for hydroxy-Y base isolated from rat liver phenylalanine tRNA.
Itaya, Taisuke,Watanabe, Nobuhide,Mizutani, Akemi
p. 4043 - 4046
(2007/10/02)

SYNTHESIS OF (S)-(-)-WYBUTINE, THE FLUORESCENT MINOR BASE FROM YEAST PHENYLALANINE TRANSFER RIBONUCLEIC ACIDS
The Wittig reaction of 1-benzyl-7-formylwye (12) with (R)-ethyl>triphenylphosphonium chlorid (8) followed by successive methylation and reduction gave (-)-wybutine .
Itaya, Taisuke,Mizutani, Akemi
p. 347 - 350
(2007/10/02)