- Structural and spectroscopic investigation on a new potentially bioactive di-hydrazone containing thiophene heterocyclic rings
-
Hydrazones and several substituted hydrazones are associated with a broad spectrum of biological activities, as well as compounds containing the thiophene ring. In this context, a novel di-hydrazone derived from 2-thiophenecarboxylic acid hydrazide was sy
- Nogueira, Vanessa De S.,Ramalho Freitas, Maria Clara,Cruz, Wellington S.,Ribeiro, Tatiana S.,Resende, Jackson A.L.C.,Rey, Nicolás A.
-
-
Read Online
- Microcrystal induced emission enhancement of a small molecule probe and its use for highly efficient detection of 2,4,6-trinitrophenol in water
-
In this contribution, we reported a very simple and small molecule material, 2,5-dimethoxyterephthalaldehyde (DMA). It exhibited a relatively weak fluorescence in solution, while showed a steadily increased green fluorescence with typical aggregation- ind
- Liu, Huan,Fu, Yanyan,Xu, Wei,He, Qingguo,Cao, Huimin,Liu, Guohua,Cheng, Jiangong
-
-
Read Online
- Synthesis of novel tetra- and pentacyclic aza-cage systems
-
A novel route to substituted pentacyclic lactams and tetracyclic amides from bis(bromomethyl) and bis(chloromethyl) substituted pentacyclo[5.4.0.02,6.03,10.05,9]undeca-8, 11-diones is reported.
- Sudhir, Uma,Rath, Nigam P,Nair, Mangalam S
-
-
Read Online
- Synthesis of a novel chiral DA-TD covalent organic framework for open-tubular capillary electrochromatography enantioseparation
-
Herein, a novel chiral covalent organic framework, DA-TD COF, with good chemical/thermal stability was synthesized and used as a chiral stationary phase for open-tubular capillary electrochromatography enantioseparation. The DA-TD COF coated capillary exh
- Chen, Hongli,Chen, Xingguo,Lv, Wenjuan,Pan, Congjie,Wang, Guoxiu
-
supporting information
p. 403 - 406
(2022/01/19)
-
- Real-time tracking of lipid droplets interactions with other organelles by a high signal/noise probe
-
Investigating the interactions between lipid droplets (LDs) and other organelles are greatly significant to the in-depth understand the physiology and pathology of LDs. Despite of commercial LDs probes available, the ER and other membrane structures are a
- Ren, Wei,Wang, Dong,Huang, Wei,Li, Jiajia,Tian, Xiaohe,Liu, Zhengjie,Han, Guangmei,Liu, Bianhua,Han, Ming-Yong,Zhang, Zhongping,Zhang, Ruilong
-
-
- A novel bifunctional-group salamo-like multi-purpose dye probe based on ESIPT and RAHB effect: Distinction of cyanide and hydrazine through optical signal differential protocol
-
A novel bifunctional-group multi-purpose dye probe p-TNS has been designed and synthesized. The probe p-TNS has unique excited-state intramolecular proton transfer (ESIPT) and resonance-assisted hydrogen bonding (RAHB) coupled system, was confirmed to detect cyanide and hydrazine by blocking the ESIPT effect. Cyanide can change the fluorescence of the solution from bright green to orange-red (116 nm Stokes shift), while hydrazine causes the bright green fluorescence to be quenched. The recognition mechanism of the probe p-TNS to CN? and N2H4 was proposed reasonably through spectral characterizations and theoretical calculations. Combined with theoretical calculations, it was speculated that the solvent dependence may be caused by the ICT effect in the molecule. The probe p-TNS could be prepared into test strips for the detection of cyanide and hydrazine. In addition, the probe molecule can also be used to detect trace amounts of cyanide in agricultural products, and respond to gaseous hydrazine by direct contact, indicating that the probe p-TNS has good practical application prospects. Therefore, this molecular framework provides a new way of thinking about detecting multiple target substances.
- Chen, Zhuang-Zhuang,Deng, Yun-Hu,Zhang, Ting,Dong, Wen-Kui
-
supporting information
(2021/06/29)
-
- Fluorescent dye for labeling virus, preparation method and application
-
The invention provides a fluorescent dye for marking viruses. Tetrazolyl is added on AIE fluorescent dye molecules. The fluorescent dye has high fluorescence labeling efficiency, is convenient for real-time tracking analysis of live viruses, and is suitab
- -
-
Paragraph 0028; 0074-0076
(2021/06/23)
-
- Rational Fabrication of Crystalline Smart Materials for Rapid Detection and Efficient Removal of Ozone
-
Traditional ozone sensing and removal materials still suffer from high energy consumption and low efficiency. Thus, seeking new ozone-responsive materials with high efficiency and broad working conditions is of great significance. Herein, we first develop
- Yan, Dong,Wang, Zhifang,Cheng, Peng,Chen, Yao,Zhang, Zhenjie
-
supporting information
p. 6055 - 6060
(2021/02/01)
-
- Metalloporphyrin and Ionic Liquid-Functionalized Covalent Organic Frameworks for Catalytic CO2Cycloaddition via Visible-Light-Induced Photothermal Conversion
-
We report the construction of a porphyrin and imidazolium-ionic liquid (IL)-decorated and quinoline-linked covalent organic framework (COF, abbreviated as COF-P1-1) via a three-component one-pot Povarov reaction. After post-synthetic metallization of COF-P1-1 with Co(II) ions, the metallized COF-PI-2 is generated. COF-PI-2 is chemically stable and displays highly selective CO2 adsorption and good visible-light-induced photothermal conversion ability (ΔT = 26 °C). Furthermore, the coexistence of Co(II)-porphyrin and imidazolium-IL within COF-PI-2 has guaranteed its highly efficient activity for CO2 cycloaddition. Of note, the needed thermal energy for the reactions is derived from the photothermal conversion of the Co(II)-porphyrin COF upon visible-light irradiation. More importantly, the CO2 cycloaddition herein is a "window ledge"reaction, and it can proceed smoothly upon natural sunlight irradiation. In addition, a scaled-up CO2 cycloaddition can be readily achieved using a COF-PI-2@chitosan aerogel-based fixed-bed model reactor. Our research provides a new avenue for COF-based greenhouse gas disposal in an eco-friendly and energy- and source-saving way.
- Ding, Luo-Gang,Yao, Bing-Jian,Wu, Wen-Xiu,Yu, Zhi-Gao,Wang, Xiao-Yu,Kan, Jing-Lan,Dong, Yu-Bin
-
supporting information
p. 12591 - 12601
(2021/08/24)
-
- Interlayer Shifting in Two-Dimensional Covalent Organic Frameworks
-
Layer-stacking structures are very common in two-dimensional covalent organic frameworks (2D COFs). While their structures are normally determined under solvent-free conditions, the structures of solvated 2D COFs are largely unexplored. We report herein t
- Kang, Chengjun,Zhang, Zhaoqiang,Wee, Vanessa,Usadi, Adam K.,Calabro, David C.,Baugh, Lisa Saunders,Wang, Shun,Wang, Yuxiang,Zhao, Dan
-
supporting information
p. 12995 - 13002
(2020/09/01)
-
- Photocatalytic Molecular Oxygen Activation by Regulating Excitonic Effects in Covalent Organic Frameworks
-
Excitonic effects caused by Coulomb interactions between electrons and holes play subtle and significant roles on photocatalysis, yet have been long ignored. Herein, porphyrinic covalent organic frameworks (COFs, specifically DhaTph-M), in the absence or presence of different metals in porphyrin centers, have been shown as ideal models to regulate excitonic effects. Remarkably, the incorporation of Zn2+ in the COF facilitates the conversion of singlet to triplet excitons, whereas the Ni2+ introduction promotes the dissociation of excitons to hot carriers under photoexcitation. Accordingly, the discriminative excitonic behavior of DhaTph-Zn and DhaTph-Ni enables the activation of O2 to 1O2 and O2?-, respectively, under visible light irradiation, resulting in distinctly different activity and selectivity in photocatalytic terpinene oxidation. Benefiting from these results, DhaTph-Ni exhibits excellent photocatalytic activity in O2?-engaged hydroxylation of boronic acid, while DhaTph-Zn possesses superior performance in 1O2-mediated selective oxidation of organic sulfides. This work provides in-depth insights into molecular oxygen activation and opens an avenue to the regulation of excitonic effects based on COFs.
- Qian, Yunyang,Li, Dandan,Han, Yulan,Jiang, Hai-Long
-
supporting information
p. 20763 - 20771
(2020/12/23)
-
- Reaction Environment Modification in Covalent Organic Frameworks for Catalytic Performance Enhancement
-
Herein, we show how the spatial environment in the functional pores of covalent organic frameworks (COFs) can be manipulated in order to exert control in catalysis. The underlying mechanism of this strategy relies on the placement of linear polymers in the pore channels that are anchored with catalytic species, analogous to outer-sphere residue cooperativity within the active sites of enzymes. This approach benefits from the flexibility and enriched concentration of the functional moieties on the linear polymers, enabling the desired reaction environment in close proximity to the active sites, thereby impacting the reaction outcomes. Specifically, in the representative dehydration of fructose to produce 5-hydroxymethylfurfural, dramatic activity and selectivity improvements have been achieved for the active center of sulfonic acid groups in COFs after encapsulation of polymeric solvent analogues 1-methyl-2-pyrrolidinone and ionic liquid.
- Sun, Qi,Tang, Yongquan,Aguila, Briana,Wang, Sai,Xiao, Feng-Shou,Thallapally, Praveen K.,Al-Enizi, Abdullah M.,Nafady, Ayman,Ma, Shengqian
-
supporting information
p. 8670 - 8675
(2019/05/07)
-
- Pore Environment Control and Enhanced Performance of Enzymes Infiltrated in Covalent Organic Frameworks
-
In the drive toward green and sustainable methodologies for chemicals manufacturing, biocatalysts are predicted to have much to offer in the years to come. That being said, their practical applications are often hampered by a lack of long-term operational stability, limited operating range, and a low recyclability for the enzymes utilized. Herein, we show how covalent organic frameworks (COFs) possess all the necessary requirements needed to serve as ideal host materials for enzymes. The resultant biocomposites of this study have shown the ability boost the stability and robustness of the enzyme in question, namely lipase PS, while also displaying activities far outperforming the free enzyme and biocomposites made from other types of porous materials, such as mesoporous silica and metal-organic frameworks, exemplified in the kinetic resolution of the alcohol assays performed. The ability to easily tune the pore environment of a COF using monomers bearing specific functional groups can improve its compatibility with a given enzyme. As a result, the orientation of the enzyme active site can be modulated through designed interactions between both components, thus improving the enzymatic activity of the biocomposites. Moreover, in comparison with their amorphous analogues, the well-defined COF pore channels not only make the accommodated enzymes more accessible to the reagents but also serve as stronger shields to safeguard the enzymes from deactivation, as evidenced by superior activities and tolerance to harsh environments. The amenability of COFs, along with our increasing understanding of the design rules for stabilizing enzymes in an accessible fashion, gives great promise for providing "off the shelf" biocatalysts for synthetic transformations.
- Sun, Qi,Fu, Chung-Wei,Aguila, Briana,Perman, Jason,Wang, Sai,Huang, Hsi-Ya,Xiao, Feng-Shou,Ma, Shengqian
-
supporting information
p. 984 - 992
(2018/02/07)
-
- A highly selective two-photon probe with large turn-on signal for imaging endogenous HOCl in living cells
-
Hypochlorous acid (HOCl) is one of the typical reactive oxygen species (ROS), which plays a crucial role in the immune system, and is involved in many neurodegenerative disorders, such as ischemic stroke, Alzheimer's, and Parkinson's disease. A two-photon
- Cao, Jingjing,Jiang, Dong-Ming,Ren, Xin,Li, Ting,Gong, Xiao-Ting,Yang, Yong-Rui,Xu, Zhu-Guo,Sun, Chun-Lin,Shi, Zi-Fa,Zhang, Shengxiang,Zhang, Hao-Li
-
p. 279 - 286
(2017/07/18)
-
- Electrochemistry and spectroelectrochemistry of a novel selenophene-based monomer
-
A stereocontrolled synthesis of a novel selenophene-based monomer namely (E,E)-1,4-dimethoxy-2,5-bis[2-(selenophen-2-yl)ethenyl]benzene has been successfully performed starting from 1,4-dimethoxybenzene. Its spectra, electrochemistry and polymerization ha
- Data, Przemyslaw,Lapkowski, Mieczyslaw,Motyka, Radoslaw,Suwinski, Jerzy
-
scheme or table
p. 567 - 572
(2012/03/10)
-
- Efficient dichloromethylation of some aromatic hydrocarbons catalyzed by a new ionic liquid [C12minPEG800]br under homogeneous catalysis in aqueous media
-
A series of new imidazolium-type ionic liquids based on polyethylene glycol have been prepared. The new recyclable temperature-dependant phase-separation system comprised of [C12minPEG800]Br and methylcyclohexane was also developed and successfully applied to the dichloromethylation of some aromatic hydrocarbons to prepare dichloromethyl-substituted hydrocarbons in excellent yields. The ionic liquid could be excellent recycled without any apparent loss of catalytic activity and little loss of weight even after 8 times recycling.
- Hu,Liu,Lu,Lu,Ge,Zhang
-
experimental part
p. 131 - 141
(2012/01/03)
-
- 2,5-diformylbenzene-1,4-diol: A versatile building block for the synthesis of ditopic redox-active schiff base ligands
-
2,5-Diformylbenzene-1,4-diol (5) is a well-suited starting compound for the preparation of ditopic hydroquinone-based ligands. Here, we report an optimized synthesis of 5 which improves the overall yield from published 7 % to 42 %. Three new ditopic Schiff base ligands, 2,5-[iPr2N(CH 2)2N=CH]2-1,4-(OH)2-C 6H2 (8), 2,5-(pyCH2N=CH)2-1,4-(OH) 2-C6H2 (9), and 2,5-[py(CH2) 2N=CH]2-1,4-(OH)2-C6H2 (10), have been synthesized from 5 and structurally characterized by X-ray crystal structure analysis (py = 2-pyridyl).
- Kretz, Tonia,Bats, Jan Willem,Lerner, Hans-Wolfram,Wagner, Matthias
-
-
- Scope and Limitations of a New Highly Selective Synthesis of Unsymmetrical Monomers for the Synthesis of Precursors toward Poly(arylenevinylene)s
-
In our laboratory a precursor route to poly(p-phenylenevinylene) derivatives is developed in which unsymmetrically substituted p-xylene derivatives, possessing a benzylic sulfinylalkyl group, are used as monomers. Because of this unsymmetry, we were forced to investigate thoroughly the synthesis of these sulfoxides, as we start from symmetric and readily accessible molecules, namely, bis(halomethyl)-p-xylene derivatives. In a former publication, a new extremely effective route for the production of these unsymmetrically substituted sulfinyl monomers was presented. This paper expands upon these previously reported results. To examine the scope and limitations of this elegant route, this new method was applied to the synthesis of various derivatives not included in the initial work.
- van der Borght, Michael,Vanderzande, Dirk,Adriaensens, Peter,Gelan, Jan
-
p. 284 - 289
(2007/10/03)
-
- Quinone-capped Porphyrins: Synthesis and some Chemical Properties
-
The 2,5-bis(hydroxyethyl) and 2,5-bis(hydroxypropyl) derivatives of hydroquinone bis(methoxymethyl) ether have been synthesised and used to 'cap' mesoporphyrin-II.Deprotection, oxidation, and metallation gave the title compounds.Several anomalous reactivi
- Ganesh, K. Nagappa,Sanders, Jeremy K. M.
-
p. 1611 - 1616
(2007/10/02)
-