- INHIBITORS OF METALLO-BETA-LACTAMASES
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The present invention relates to compounds of Formula (I) that function as inhibitors of bacterial metallo-beta-lactamases. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of a bacterial infection. (Formula (I))
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Paragraph 00163; 00164
(2018/12/13)
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- Porphyrins with Exocyclic Rings. 1. Chemistry of 4,5,6,7-Tetrahydro-1H-indoles: Synthesis of Acetoxy Derivatives, Dihydroindoles, and Novel Porphyrins with Four Exocyclic Rings
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A variety of 4,5,6,7-tetrahydro-1H-indoles (THI's) and 4-oxo-4,5,6,7-tetrahydro-1-indoles (4-oxoTHI's) have been synthesized from cyclohexanone and 1,3-cyclohexanedione, respectively.The THI's reacted regioselectively with lead tetraacetate in acetic acid
- Lash, Timothy D.,Bladel, Karla A.,Shiner, Craig M.,Zajeski, Donna L.,Balasubramaniam, Rajiv P.
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p. 4809 - 4820
(2007/10/02)
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- Photochemical Heterocyclization of Functionalized Dienamines
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A series of functionalized dienamines were prepared by base-catalyzed isomerisation of N-vinylaziridines.Photochemical cyclization of these N-substituted dienamines yielded predominantly pyrroline derivatives.
- Gelas-Mialhe, Yvonne,Mabiala, Gaston,Vessiere, Roger
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p. 5395 - 5400
(2007/10/02)
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