cas 37989-92-7, 4'-(2-FLUOROPHENYL)PROPIOPHENONE | Articles data ｜lookchem

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37989-92-7

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Synthesis of Aryl Trimethylstannane via BF3·OEt2-Mediated Cross-Coupling of Hexaalkyl Distannane Reagent with Aryl Triazene at Room Temperature
BF3·OEt2-mediated cross-coupling of (SnMe3)2 with aryl triazene offers a new strategy for the synthesis of aryl stannane. A variety of synthetically useful aryl trimethylstannanes were produced in moderate to good yields with this metal-free approach. One-pot sequential Stille cross-coupling with different aryl bromides provides a short entry to both symmetrical and unsymmetrical biaryl compounds.
Mao, Shuai,Chen, Zhengkai,Wang, Lu,Khadka, Daulat Bikram,Xin, Minhang,Li, Pengfei,Zhang, San-Qi
p. 463 - 471
(2019/01/10)

Design, Synthesis, and Characterization of Brequinar Conjugates as Probes to Study DHODH Inhibition
Brequinar, a potent dihydroorotate dehydrogenase (DHODH) inhibitor, has been evaluated in multiple clinical trials as a potential treatment for cancer. To further understand brequinar-based DHODH inhibition and DHODH′s therapeutic relevance in cancer, we
Madak, Joseph T.,Cuthbertson, Christine R.,Chen, Wenmin,Showalter, Hollis D.,Neamati, Nouri
supporting information
p. 13875 - 13878
(2017/09/18)

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Chemical Properties

Melting Point: 76-77
Boiling Point: 334.1°Cat760mmHg
Flash Point:138.5°C
Density: 1.102g/cm³
Storage Temp.:Sealed in dry,Room Temperature
PSA: 17.07000
LogP: 4.08540

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