The present invention is directed to compounds of Formula I: that are potassium channel modulators and pharmaceutical compositions thereof. The present invention is further directed to methods of treatment using the compounds and pharmaceutical compositions of the invention. The present invention is still further directed to synthetic processes for producing the compounds of the invention.
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Page/Page column 30
(2008/06/13)
Aryne and SNAr Reactions of Polyhalogenobenzenes. 6. Synthesis of Benzofurans
The scope and limitations of the one-pot synthesis of benzofurans by aryne condensations of the cyclic ketone enolates with dihalogenobenzenes in the presence of the complex base NaNH2-t-BuONa were studied.It is shown that this method is of interest for t
Bachelet, Jean-Pierre,Caubere, Paul
p. 234 - 238
(2007/10/02)
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