SPIRO CONDENSED PIPERIDNES AS MODULATORS OF MUSCARINIC RECEPTORS
The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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Page/Page column 49
(2008/06/13)
SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS
The invention relates to substituted 1-propiolylpiperazines according to formula (I), to a method for the production thereof, medicaments containing said compounds and to the use thereof in the production of medicaments. In formula (I), X represents N or C-R2 and n corresponds to a value between 0-8.
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Page/Page column 107
(2010/02/15)
(R,R) AND (S,S) 2,5-DIAZABICYCLO [2,2,1]HEPTANE DERIVATIVES
Compounds of the Formulae I or II STR1 wherein Z and R 1, are as described herein which compounds are muscarinic agonists useful in treating central cholinergic disfunction and pharmaceutical compositions containing the compounds.
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(2008/06/13)
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