Synthesis of (Aryloxy)propanolamines via a Palladium-Promoted Oxyamination
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Baeckvall, Jan-E.,Bystroem, Styrbjoern E.
p. 1126 - 1128
(2007/10/02)
Prostanoid compounds and compositions
Prostanoid compounds are described having the formula: STR1 where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH=CH-- or --(CH2)2 --; R is alkyl having a terminal --COOH or ester grup; and Y is amino or substituted amino, particularly heterocyclic amino. The compounds have bronchodilator activity and/or inhibit blood platelet aggregation. The preparation and pharmaceutical formulation of the compounds is also described.
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(2008/06/13)
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