cas 40298-71-3, BOC-TYR(2,6-DI-CL-BZL)-OH | Articles data ｜lookchem

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40298-71-3

Articles about 40298-71-3Total 4 be found

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Synthesis and biological activity of N-substituted aminocarbonyl-1,3- dioxolanes as VLA-4 antagonists
A novel set of compounds with a 1,3-dioxolane ring which acts as a proline bioisostere have been successfully designed as VLA-4 receptor antagonists. Compounds (18e), (28j), and (35g) were shown to have high receptor affinities.
Rehman, Abdul,Soni, Ajay,Naik, Keshav,Nair, Sreeji,Palle, Venkata P.,Dastidar, Sunanda,Ray, Abhijit,Alam,Salman, Mohammad,Cliffe, Ian A.,Sattigeri, Viswajanani
scheme or table
p. 5514 - 5520
(2011/01/12)

A simple method for the alkaline hydrolysis of esters
A very mild and rapid procedure for the efficient alkaline hydrolysis of esters in non-aqueous conditions has been developed, by the use of dichloromethane/methanol (9:1) as solvent. This method conveniently provides both carboxylic acids and alcohols from the corresponding esters and sodium hydroxide in a few minutes at room temperature. A plausible reaction mechanism is proposed.
Theodorou, Vassiliki,Skobridis, Konstantinos,Tzakos, Andreas G.,Ragoussis, Valentine
p. 8230 - 8233
(2008/03/14)

tert-butoxycarbonylation of amino acids and their derivatives: N-tert-butoxycarbonyl-L-phenylalanine
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Keller, Oskar,Keller, Walter E.,Van Look, Gert,Wersin, Gernot
p. 160 - 160
(2017/06/01)

Studies on polypeptides XXXIII. Semisynthetic ribonuclease analogues. The role of histidine-119
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Serdijn,Hoes,Raap,Kerling
p. 349 - 352
(2007/10/02)

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Chemical Properties

Melting Point: 128-130oC
Boiling Point: 594°Cat760mmHg
Flash Point:313°C
Density: 1.305g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 0mmHg at 25°C
Refractive Index: 1.575
PKA: 2.98±0.10(Predicted)
BRN: 3573263
PSA: 84.86000
LogP: 5.48370

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