The invention relates to a method for synthesizing riociguat. The method includes the following steps: 1, a compound 1-(2-fluorobenzyl)-1H-[3,4-b] pyridine derivative-3-formamidine hydrochloride (1) and a compound benzeneazomalononitrile (2) are reacted i
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Paragraph 0029-0031
(2017/03/28)
Preparation method and application of pyrazolo[3, 4-b]pyridine compound intermediate
The invention provides a preparation method and application of a pyrazolo[3, 4-b]pyridine compound intermediate. Specifically, the intermediate structure is shown as formula IV, wherein the groups are defined as the specification and claims. The intermedi
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(2016/10/17)
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