- Electro-Oxidative Selective Esterification of Methylarenes and Benzaldehydes
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A mild and green electro-oxidative protocol to construct aromatic esters from methylarenes and alcohols is herein reported. Importantly, the reaction is free of metals, chemical oxidants, bases, acids, and operates at room temperature. Moreover, the design of the electrolyte was found critical for the oxidation state and structure of the coupling products, a rarely documented effect. This electro-oxidative coupling process also displays exceptional tolerance of many fragile easily oxidized functional groups such as hydroxy, aldehyde, olefin, alkyne, as well as neighboring benzylic positions. The enantiomeric enrichment of some chiral alcohols is moreover preserved during this electro-oxidative coupling reaction, making it overall a promising synthetic tool.
- Yu, Congjun,?zkaya, Bünyamin,Patureau, Frederic W.
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supporting information
p. 3682 - 3687
(2021/02/01)
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- Porphyrin sensitizers containing an auxiliary benzotriazole acceptor for dye-sensitized solar cells: Effects of steric hindrance and cosensitization
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Dye-sensitized solar cells (DSSCs) have attracted intensive attention in developing photovoltaic devices for employing solar energy. For developing panchromatic and efficient porphyrin sensitizers, it has been demonstrated to be an effective approach to i
- Song, Heli,Tang, Weiqiang,Zhao, Shuangliang,Liu, Qingyun,Xie, Yongshu
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p. 323 - 331
(2018/04/12)
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- Design and synthesis of potent amido- and benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV inhibitors
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The cis-3-amino-4-(2-cyanopyrrolidide)-pyrrolidine template has been shown to afford low nanomolar inhibitors of human DPP-IV that exhibit a robust PK/PD profile. An X-ray co-crystal structure of 5 confirmed the proposed mode of binding. The potent single
- Corbett,Dirico,Song,Boscoe,Doran,Boyer,Qiu,Ammirati,VanVolkenburg,McPherson,Parker,Cox
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p. 6707 - 6713
(2008/09/17)
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