Synthesis of [C2H3]methotrexate and [C2H3]7-hydroxymethotrexate
Stable label analogues of methotrexate (MTX) and 7-hydroxymethotrexate (7-OH-MTX) were required for use as internal standards for LC/MS quantitation. A minimum incorporation of stable isotopes to produce a mass increase of 3 in the non-glutamate derived p
Elmore, Charles S.,Dean, Dennis C.,Zhang, Yong,Gibson, Carter,Jenkins, Herb,Jones, Allen N.,Melillo, David G.
p. 29 - 36
(2007/10/03)
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