Novel class of potent 4-arylalkyl substituted 3-isoxazolol GABAA antagonists: Synthesis, pharmacology, and molecular modeling
A number of analogues of the low-efficacy partial GABAA agonist 5-(4-piperidyl)-3-isoxazolol (4-PIOL, 5), in which the 4-position of the 3-isoxazolol ring was substituted by different groups, were synthesized and tested as GABAA rece
Fr?lund, Bente,J?rgensen, Anne T.,Tagmose, Lena,Stensb?l, Tine B.,Vestergaard, Henrik T.,Engblom, Christine,Kristiansen, Uffe,Sanchez, Connie,Krogsgaard-Larsen, Povl,Liljefors, Tommy
p. 2454 - 2468
(2007/10/03)
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