- BIS-ARYL ETHERS CONTAINING N-ACYL AZETIDINE AS EGFR/HER2 INHIBITORS
-
The invention provides compounds and pharmaceutical compositions thereof, which are useful for inhibiting EGFR and erbB2 activity, as well as methods for using such compounds to treat cancer associated with mutant EGFR and erbB2 activity.
- -
-
-
- Quinazoline derivatives
-
A compound of the formula (I) or a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, an optically active compound thereof, a racemate thereof or a diastereomer mixture thereof has a superior tyrosine-specific protein kinase inhibitory activity and is useful as a pharmaceutical agent, particularly as an agent for the prophylaxis or treatment of various cancers, psoriasis or diseases caused by arteriosclerosis, and the like.
- -
-
Page/Page column 49
(2010/02/07)
-