The present invention relates to technetium imaging agents comprising radiolabeled c-Met binding peptides suitable for SPECT or PET imaging in vivo. The c-Met binding peptides are labelled via chelator conjugates. Also disclosed are pharmaceutical compositions, methods of preparation of the agents and compositions, plus methods of in vivo imaging using the compositions, especially for use in the diagnosis of cancer.
-
Page/Page column 21
(2016/03/12)
APOPTOSIS IMAGING AGENTS BASED ON LANTIBIOTIC PEPTIDES
The present invention relates to radiopharmaceutical imaging in vivo of apoptosis. The invention provides imaging agents which target apoptotic cells via selective binding to the aminophospholipid phosphatidylethanolamine (PE), which is exposed on the surface of apoptotic cells. The radiopharmaceuticals comprise radiometal complexes of chelator conjugates of PE-binding peptides. Also provided are pharmaceutical compositions, kits and methods of in vivo imaging.
-
(2013/07/31)
More Articles about upstream products of 489427-21-6
Get Best Price for489427-21-64-{5-(2-hydroxyimino-1,1-dimethyl-propylamino)-3-[2-(2-hydroxyimino-1,1-dimethyl-propylamino)-ethyl]-pentylcarbamoyl}-thiobutyric acid 2,3,5,6-tetrafluoro-phenyl ester