- Method for synthesizing beta-bromoacetate compounds
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The invention discloses a method for synthesizing beta-bromoacetate compounds. The method comprises the following steps: reacting in an organic solvent at a temperature of 15-60 DEG C for 1-6 hours bytaking styrene compounds shown as a formula I as raw ma
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Paragraph 0050; 0051
(2019/01/22)
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- A simple and facile method for regio- and stereoselective bromoformyloxylation and bromoacetoxylation of olefins using NH4Br and oxone
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A mild and efficient protocol for the preparation of bromoformates as well as bromoacetates from olefins using NH4Br and oxone in nucleophile sources (DMF or DMA) without employing catalyst at room temperature is described. This method is facile, environmentally friendly and cost effective. A variety of terminal, internal and cyclic alkenes reacted smoothly to give the corresponding bromoformate and acetate products in good to excellent yields. Moreover, 1,2-disubstituted olefins provided moderate to excellent diastereoselectivity.
- Naresh, Mameda,Swamy, Peraka,Arun Kumar, Macharla,Mahender Reddy, Marri,Srujana, Kodumuri,Narender, Nama
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supporting information
p. 3926 - 3933
(2014/07/08)
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- A simple and efficient bromoformyloxylation and bromoacetoxylation reaction using TsNBr2
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Bromoformyloxylation and bromoacetoxylation of olefins proceed smoothly and instantaneously in the presence of N,N-dibromo-p-toluene sulfonamide without any catalyst. The one step reactions can be carried out with all kinds of olefins in high yield and hi
- Saikia, Indranirekha,Rajbongshi, Kamal Krishna,Phukan, Prodeep
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supporting information; experimental part
p. 758 - 761
(2012/03/08)
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- Comparative study of the vicinal functionalization of olefins with 2:1 bromide/bromate and iodide/iodate reagents
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A comparative evaluation was made on the syntheses of vicinal halohydrins, halo methyl ethers, and halo acetates from olefins using 2:1 Br-/BrO3- and I-/IO3- reagents. In many cases both reagents afforded products selectively in high yields. The highest halogen atom efficiencies attained were 97% and 93% for Br-/BrO3- and I-/IO3-, respectively. Of the two reagents, I-/IO3- was established to be the preferred reagent for vicinal functionalization of linear alkenes and also for halo acetate preparation. However, only Br-/BrO3- was effective for vicinal functionalization of trans-stilbene and chalcones.
- Agrawal, Manoj K.,Adimurthy, Subbarayappa,Ganguly, Bishwajit,Ghosh, Pushpito K.
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experimental part
p. 2791 - 2797
(2009/08/08)
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- Dimethylformamide, dimethylacetamide and tetramethylguanidine as nucleophilic organocatalysts for the transfer of electrophilic bromine from N-bromosuccinimide to alkenes
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Dimethylformamide, dimethylacetamide and tetramethylguanidine were found to act as increasingly active catalysts for the bromolactonisation of γ,δ- and δ,ε-unsaturated carboxylic acids with N-bromosuccinimide. The catalysts are readily removed in the work
- Ahmad, Simon M.,Braddock, D. Christopher,Cansell, Gemma,Hermitage, Stephen A.
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p. 915 - 918
(2008/02/04)
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- Amidines as potent nucleophilic organocatalysts for the transfer of electrophilic bromine from N-bromosuccinimide to alkenes
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(±)-iso-Amarine is a potent organocatalyst at 1 mol % loading for both the bromoacetoxylation of alkenes with added acetic acid and bromolactonisation of unsaturated carboxylic acids with stoichiometric NBS as the electrophilic bromine source. A simple br
- Ahmad, Simon M.,Braddock, D. Christopher,Cansell, Gemma,Hermitage, Stephen A.,Redmond, Joanna M.,White, Andrew J.P.
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p. 5948 - 5952
(2008/02/10)
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- Bromochlorination of Alkenes with Dichlorobromate(1-) Ion. V. Regio- and Stereochemistry for the Bromochlorination of Styrene Derivatives with Dichlorobromate(1-) Ion in Protic Solvents
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The bromochlorination of styrene derivatives with tetrabutylammonium dichlorobromate(1-) (1) in such protic solvents as acetic acid and methanol gives the corresponding bromo chloro adducts along with substantial amounts of solvent-incorporated products i
- Negoro, Takeshi,Ikeda, Yoshitsugu
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p. 3519 - 3522
(2007/10/02)
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- TELLURIUM DIOXIDE OXIDATION OF STILBENE DIBROMIDES TO BENZILS
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Tellurium dioxide reacts with stilbene dibromides in hot acetic acid to give benzils in good to moderate yields.
- Suzuki, Hitomi,Ninomiya, Keiji,Inouye, Masahiko
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p. 821 - 822
(2007/10/02)
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