cas 49653-17-0, ETHYL 2-ETHOXY-2-HYDROXYACETATE | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
49653-17-0

Articles about 49653-17-0Total 5 be found

Article title
Article abstract
Author
Journal number and time
Download

Evaluation of several routes to advanced pregabalin intermediates: Synthesis and enantioselective enzymatic reduction using ene-reductases
This publication describes the evaluation of four synthetic routes to the advanced pregabalin (Lyrica) intermediate 7. Asymmetric reduction of (E)-7 with an ene-reductase (OPR1 from Lycopersicon esculentum) gave a saturated cyanoester intermediate 5 with the desired S stereocenter in ≥99% ee. OPR1 also catalyzed the reduction of (Z)-7 to (S)-5, but with lower conversion and selectivity.
Debarge, Sebastien,McDaid, Paul,O'Neill, Pat,Frahill, James,Wong, John W.,Carr, Donncha,Burrell, Adam,Davies, Simon,Karmilowicz, Mike,Steflik, Jeremy
p. 109 - 121
(2014/05/20)

CROSSLINKING AGENT, CROSSLINKED POLYMER, AND USES THEREOF
There is provided a novel crosslinking agent for use in crosslinked polymer fabrication, specifically a crosslinking agent containing at least one compound selected from glyoxylate and a glyoxylic acid ester derivative represented by the following general formula (1): wherein R1 and R2 each independently represents an alkyl group having 1 to 10 carbon atoms and R3 represents a hydrogen atom or an alkyl group having 1 to 10 carbon atoms.
-
Page/Page column 20

(2010/08/22)

Synthesis and enantioselective hydrogenation of α-acyloxyacrylates
Numerous α-acyloxyacrylates have been prepared by Wittig-Horner reaction of aldehydes and ethyl 2-acyloxy-2-(diethoxyphosphoryl)acetates which were easily obtained from glyoxylic acid hydrate. The formed α-acyloxyacrylates were subsequently hydrogenated enantioselectively using Rh-DIPAMP and Ru-BINAP (ee = 82-98%) to furnish the corresponding α-acyloxycarboxylates.
Schmidt,Langner,Kirschbaum,Braun
p. 1138 - 1140
(2007/10/02)

ENZYLATICALLY CLEAVABLE ALKOXYCARBONYL ETHOXYMETHYL ESTERS FOR REVERSIBLE BLOCKING OF CARBOXYL GROUPS
By O-alkylation carboxylic acids with α-bromo-α-ethoxy acetates new alkoxycarbonyl ethoxymethyl esters (ACEM esters) were synthesised in a simple route.The ACEM blocking group can be casily cleft by esterases.
Klemm, D.,Geschwend, G.
p. 2337 - 2348
(2007/10/02)

α-BROMO-α-ETHOXY-ACETIC DERIVATIVES AS NEW ALKYLATING REAGENTS
A convenient synthesis of new α-bromo-α-ethoxy-acetic acid alkylating reagents, intermediates for the synthesis of enzymatically cleavable alkoxycarbonyl ethoxymethyl esters, is described.
Klemm, D.,Geschwend, G.
p. 1431 - 1438
(2007/10/02)

More Articles about upstream products of 49653-17-0

More Articles about downstream products of 49653-17-0

Chemical Properties

Melting Point: 134.5-136.0 °C
Boiling Point: 174.9°Cat760mmHg
Flash Point:61.1°C
Density: 1.095g/cm³
Solubility:Chloroform, Ethanol, Methanol
Vapor Pressure: 0.365mmHg at 25°C
PKA: 11.24±0.20(Predicted)
PSA: 55.76000
LogP: -0.09560

Show more

Global suppliers and manufacturers of 49653-17-0total 10 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Dayang Chem (Hangzhou) Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 3.0-3.0 / Kilogram
Main Products:994
Country:

Henan Tianfu Chemical Co., Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 1000.0-1000.0 / Kilogram
Main Products:67
Country:

Shandong Mopai Biotechnology Co., LTD
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:60
Country:

Antimex Chemical Limied
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:163
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

Amadis Chemical Co., Ltd.
Business Type:Lab/Research institutions
Min Order:10 Milligram
FOB Price:No Data
Main Products:1
Country:

Shanghai united Scientific Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Finetech Industry Limited
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Wuxi Morality Chemical Co., Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Chemical Co.Ltd
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 49653-17-0

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer