- Palladium-catalyzed stille-type coupling of N -acyl iminium ions with distannanes: A Multicomponent synthesis of α-amidostannanes
-
The palladium-catalyzed three-component coupling of imines, acid chlorides, and hexabutyldistannane is described. This results in the synthesis of various α-amidostannanes in good yields, without the use of strong nucleophilic organometallic reagents. The reaction is believed to proceed via a Stille-type cross coupling of an in situ-generated N-acyl iminium salt with Bu 3SnSnBu3 and reaches completion within 1 h at ambient temperature using simple, unligated Pd2dba3 as a catalyst. Combining the formation of α-amidostannanes with lithiation and carboxylation allows the overall synthesis of amino acid derivatives in two steps from imines, acid chlorides, and CO2.
- Xu, Boran,Arndtsen, Bruce A.
-
p. 843 - 846
(2014/04/03)
-
- A general method for the preparation of 5-trifluoromethylated oxazoles from α-amino acids
-
The reactions of N-acyl-N-benzyl-α-amino acids (1) or N-acylprolines (5) with trifluoroacetic anhydride in the presence of pyridine afford 5- trifluoromethyloxazoles (2 or 7) in good yields. The reaction could proceed through the transient formation of me
- Kawase, Masami,Miyamae, Hiroshi,Kurihara, Teruo
-
p. 749 - 756
(2007/10/03)
-
- Tandem 1,3-dipolar cycloadditions of muenchnones. Syntheses and molecular structures of 10-azatetracyclo[6.3.0.04,11.05,9]undecanes and azahomopentaprismane
-
Photocyclization of 10-benzyl-9,11-diphenyl-10-azatetracyclo[6.3.0.04,11.0 5,9]undeca-2,6-diene 11, prepared in one step from muenchnone 7 and cycloocta-1,3,5,7-tetraene 10, gives azahomopentaprismane 12.
- Gribble, Gordon W.,Sponholtz III, William R.,Switzer, Frank L.,D'Amato, Ferdinando J.,Byrn, Marianne P.
-
p. 993 - 994
(2007/10/03)
-
- Isothiazoles. Part IV. Cycloaddition reactions of diaryl-oxazolones and munchnones to 3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide: A new synthesis of triarylpyrroles
-
3-Diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide (3) readily reacts with oxazolones 2 and munchnones 7 affording with satisfactory yield 3-diethylamino-4,6-diaryl-3a,4-dihydro-3a-(4-methoxyphenyl)-6aH-pyrrol o[3,4-d]isothiazole 1,1-dioxides 4 an
- Baggi,Clerici,Gelmi,Mottadelli
-
p. 2455 - 2466
(2007/10/02)
-