2-Amino-6-chloro-4-(N-methylpiperazino)pyrimidines, Inhibitors of Spiroperidol Binding
A series of 30 6-chloro-2,4-diaminopyrimidines was synthesized and tested in vitro as inhibitors of spiroperidol binding.The affinity for the dopamine receptor was shown to be related to the 6-chloro-4(N-methylpiperazine)pyrimidine structure bearing a