- MANUFACTURING METHOD OF 2-SUBSTITUTED IMIDAZOLE COMPOUND
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PROBLEM TO BE SOLVED: To provide a high-yield manufacturing method of a 2-substituted imidazole which is expected to be useful as a curing agent for epoxy resins, polyurethane resins or the like, as an intermediate of various agrochemicals, antibiotics or pharmaceuticals such as anti-AIDS agents or the like, or as dye intermediates. SOLUTION: An aldehyde compound is reacted with ammonia (I) to give an imine compound, and subsequently an α,β-dicarbonyl compound and ammonia (II) are added and allowed to react with the imine compound. Preferably, the α,β-dicarbonyl compound and ammonia (II) are simultaneously added.
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(2010/02/11)
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