- Approaches to improve the solubility and availability of progesterone biotransformation by Mucor racemosus
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Substrate solubility in steroid biotransformation is critical for improving the biotransformation of hydrophobic substrates. The present investigation describes the effect of some organic solvents, polyoxyethylene sorbitan monooleate (Tween 80; surfactant
- Mohamed, Sayeda Saleh,El-Refai, Abdel-Monem Hassan,Hashem, Abdel-Gawad Mohamed,Ali, Heba Ahmed
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p. 141 - 150
(2014/06/23)
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- Pharmaceutical composition and process of treatment
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A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc. comprising administering to humans, or domesticated animals, topically and/or systemically a composition comprising a pharmaceutical carrier and at least one active compound selected from the groups, substituted alkyl zanthines, tricyclic antidepressants, organic nitrates, antihypertensives, anti-asthma agents and central nervous system depressants and combinations of certain compounds from specifically named groups of compounds.
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- Selenium-75 steroids
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Novel dimeric and monomeric selenium-75 derivatives of steroids are made by reacting a keto steroid with selenium-75 dioxide or selenious acid-Se75. The resulting diselenide dimers can be converted into monomeric compounds by the use of a cleaving reagent followed by an alkylating agent. The compounds are useful in saturation analyses such as radioimmunoassays.
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