cas 55096-26-9, Nalmefene | Articles data

Articles about 55096-26-9Total 4 be found

Novel nalmefene dimer as well as preparation method and application thereof
The invention relates to a novel nalmefene dimer compound with a structure as shown in a formula (I) or a salt thereof, and a preparation method and application of the compound, and the compound has a relatively strong inhibition effect on prostate cancer cell lines LNCaP and 22Rv1, and can be used for preparing drugs for resisting prostate cancer.
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Paragraph 0088-0090

(2021/10/13)

O-Demethylation of opioid derivatives with methane sulfonic acid/methionine: Application to the synthesis of naloxone and analogues
Naloxone 2 was obtained by demethylation of N-allylnoroxycodone 1 with methane sulfonic acid/methionine. This reagent is an excellent substitute for boron tribromide. It was used for the synthesis of analogous derivatives with variable results.
Andre,Dormoy,Heymes
p. 2313 - 2327
(2007/10/02)

Wittig-reaction processes
Disclosed are improved Wittig reaction processes wherein the Wittig reaction is conducted in an anisole containing solvent.
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(2008/06/13)

Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
An improved Wittig reaction for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone from naloxone and naltrexone utilizing an alkoxide base in an ethereal solvent.
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(2008/06/13)

Chemical Properties

Melting Point: 182-185?C
Boiling Point: 507.9±50.0 °C(Predicted)
Density: 1.38±0.1 g/cm3(Predicted)
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Sl
Storage Temp.:2-8°C
PKA: pKa 7.63(H2O) (Uncertain)
PSA: 52.93000
LogP: 2.45040

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