Synthesis of symmetrical and unsymmetrical N-aryl-substituted cyclic ureas through copper(I) iodide catalyzed Goldberg-Buchwald-Nandakumar C-N coupling reactions
The catalytic conditions of copper(I) iodide/potassium carbonate/trans-N, N′-dimethylcyclohexane-1,2-diamine, either in toluene at reflux temperature, or by heating neat at 150°C effectively promoted the C-N coupling of aryl bromides with cyclic ureas. By
Lee, Chung-Chieh,Wang, Po-Shih,Viswanath, M. Balaji,Leung, Man-Kit
p. 1359 - 1366
(2008/12/21)
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