- QUINUCLIDINES FOR MODULATING ALPHA 7 ACTIVITY
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Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating α7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.
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- NEW SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS
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The present invention relates to substituted arylsulphonylglycines of general formula (I) wherein R, X, Y and Z are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures thereof and salts thereof, which have valuable pharmacological properties, particularly the suppression of the interaction of glycogen phosphorylase a with the GL subunit of glycogen-associated protein phosphatase 1 (PP1 ), and their use as pharmaceutical compositions.
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- Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
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The present invention relates to urotensin II receptor antagonists, pharmaceutical compositions containing them and their use.
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- Synthese von natuerlichen Haloindolen via Hetero-Cope-Umlagerung von Vinyl-N-phenylhydroxamaten
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An efficient method for the synthesis of natural 4-chloro-6-methoxyindole (the promutagen from fava beans) and of the two 4,6-dibromo- and 3,4,6-tribromoindoles (produced by acorn worms, Enteropneusta) is presented.The key step is a hetero-Cope rearrangem
- Martin, Pierre
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p. 344 - 347
(2007/10/02)
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