cas 56406-50-9, 3-NITROBENZAMIDINE HYDROCHLORIDE | Articles data ｜lookchem

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56406-50-9

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Synthesis and structure of aroylamidines and N-arylbenzamidines hydrochlorides
Aroylamidines can be obtained as salts in a reaction of the corresponding arylcarbonitriles with anhydrous ethanol in the presence of dry HCl followed by treating intermediate imidoesters with alcoholic solution of ammonia. N-Arylbenzamidines are obtained by reacting benzonitrile with arylamines in the presence of AlCl3. The structure of arylamines and the reaction conditions signifi cantly affect the yield of the target product, and sometimes the very possibility of its preparation. Pleiades Publishing, Ltd., 2012.
Kuvaeva,Fedorova,Zaitsev,Yakovlev,Zakharov,Semakova
experimental part
p. 209 - 213
(2012/06/01)

SUBSTITUTED IMIDAZOTRIAZINES
The invention relates to novel substituted imidazotriazines, to methods for the production thereof, and to their use for producing medicaments for the treatment and/or prophylaxis of cancer and neurodegenerative diseases, particularly Parkinson's disease and schizophrenia.
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Page/Page column 44-45

(2010/02/06)

5-ETHYLIMIDAROTRIAZONES
The invention relates to novel 5-ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
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Page/Page column 29

(2010/02/07)

Novel heterocycles 3
The invention relates to 7-(4-tert butyl-cyclohexyl)-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
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(2008/06/13)

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Chemical Properties

Appearance/Colour :Light yellow microcrystalline powder
Melting Point: 245-248 °C(lit.)
Boiling Point: 301.7°C at 760 mmHg
Flash Point:136.3°C
Density: 1.42g/cm3
Vapor Pressure: 0.00103mmHg at 25°C
PSA: 95.69000
LogP: 3.00410

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