- Simple synthesis process of anxiolytic drug lorazepam intermediate
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The invention discloses a simple synthesis process of an anxiolytic drug lorazepam intermediate. The simple synthesis process comprises the steps of putting N-(2-chloroethyl)acetamide, triethylamine and dichloromethane into a reaction bottle; stirring the
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Paragraph 0013; 0014; 0019; 0020; 0024
(2019/05/08)
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- Process for Preparing 4-Acetyl-2,3,4,5-tetrahydro-benzo[1,4]diazepine and the Intermediates Thereof
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The present invention relates to a process for preparing 4-acetyl-2,3,4,5-tetrahydro-benzo[1,4]diazepine and the intermediates thereof. The present invention provides a compound represented by formula I and a compound represented by formula II, and proces
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Page/Page column 5
(2010/10/19)
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- PREPARATION METHODS OF 4-ACETYL-2,3,4,5-TETRAHYDRO- BENZO[1,4]DIAZEPINE AND THEIR INTERMEDIATES
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The present invention relates to a process for preparing 4-acetyl-2,3,4,5-tetrahydrobenzo[1,4]diazepine and the intermediates thereof. The present invention provides a compound represented by formula I and a compound represented by formula II, and processes for preparing 4-acetyl-2,3,4,5-tetrahydro-benzo[1,4]diazepine by using the compound represented by formula I, the compound represented by formula II and o-nitrobenzaldehyde. The invention has the advantages of the shorter synthesis steps, easily available raw materials and simple operation. Moreover, the process is economic and safe by avoiding the use of expensive and dangerous lithium aluminium hydride.
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Page/Page column 8
(2010/04/24)
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- Process for preparing quinoline compounds and products obtained therefrom
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Methods for synthesizing tetrahydroquinoline-containing compounds are provided, along with synthetic intermediates and products associated with such methods.
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Page/Page column 13-14
(2008/06/13)
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- Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT 2C receptor
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Evaluation of selected compounds from our Corporate Compound Library in a human 5-HT2C receptor binding assay led to the discovery of WAY-629, a cyclohexyl[b][1,4]benzodiazepinoindole (Ki 56nM, Emax 90%), which is selectiv
- Sabb, Annmarie L.,Vogel, Robert L.,Welmaker, Gregory S.,Sabalski, Joan E.,Coupet, Joseph,Dunlop, John,Rosenzweig-Lipson, Sharon,Harrison, Boyd
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p. 2603 - 2607
(2007/10/03)
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