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Benzodiazepine derivatives and their pharmaceutical use
There are presented novel pharmaceutically active substances which inhibit the intestinal resorption of cholesterol and which accordingly can be used in the control or prevention of atherosclerosis. These active substances are benzodiazepines of the formu
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(2008/06/13)

Benzodiazepine derivatives
This invention is directed toward pharmacologically active compounds of the formula STR1 wherein R represents a hydrogen atom or a lower alkyl group and R1 represents a hydrogen or halogen atom or a trifluoromethyl group which have the absolute configuration S at the 3-position carbon atom. Also presented is a process to produce the above benzodiazepine derivatives and pharmaceutical preparations therefor. The above benzodiazepine derivatives exhibit pronounced anthelmintic, especially schistosomicidal, activity and muscle relaxant, anticonvulsant and sedative activities.
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(2008/06/13)

Benzodiazepine derivatives
This invention is directed to pharmacologically active compounds of the formula STR1 wherein R1 represents a hydrogen atom or lower alkyl group and R2 represents a halogen atom. The compounds of formula I are optically active and have the absolute configuration S at the carbon atom in the 3-position. They exhibit anthelmintic, sedative, anticonvulsant and muscle relaxant activity. Also provided are methods for their preparation and formulations which incorporate the active compounds.
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(2008/06/13)