Microwave-assisted ring opening of epoxides: A general route to the synthesis of 1-aminopropan-2-ols with anti malaria parasite activities
A series of 1-aminopropan-2-ols were synthesized and evaluated against two strains of malaria, Plasmodium falciparum FCR3 (chloroquine-resistant) and 3D7 (chloroquine-sensitive). Microwave-assisted ring opening of epoxides (aryl and alkyl glycidyl ethers,
Robin, Aélig,Brown, Fraser,Bahamontes-Rosa, Noemí,Wu, Binghua,Beitz, Eric,Kun, Jürgen F. J.,Flitsch, Sabine L.
p. 4243 - 4249
(2008/02/12)
AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS
Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.
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Page 99
(2010/02/08)
The 1,3-diamino-propan-2-ol series. II. N-cycloalkyl and azacyclo derivatives
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Laguerre,Boyer,Carpy,Leger,Panconi,Vaugine,Cognic
p. 81 - 85
(2007/10/02)
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