A novel and convenient method for synthesizing unsymmetrical - Benzyloxycarbonyl-protected 1-amino-1-arylalkylphosphonate mixed diesters
Unsymmetrical N-benzyloxycarbonyl-protected 1-amino-1-arylalkylphosphonate mixed diesters were synthesized using a one-pot reaction involving benzyl carbamate, aromatic aldehydes and alkoxydichlorophosphine, followed by treatment with alcohols in the presence of triethylamine. The reactions were followed by 31P NMR and a mechanism is proposed.
Xu,Fu
p. 1223 - 1226
(2007/10/03)
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