cas 59382-60-4, Ethyl 2-methyl-3-nitrobenzoate | Articles data ｜lookchem

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59382-60-4

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Synthesis of symmetric diester-functionalised Troeger's base analogues
The yields of ester-functionalised Troeger's base analogues are dramatically improved by incorporating an electron-donating group on the aromatic ring and/or enhancing solubil- ity of the aniline unit. In addition to 2,8-diester compounds, 1,7-, 3,9- and 4,10-diester-functionalised Troeger's base analogues have been prepared for the first time.
Bhuiyan, M. Delower H.,Zhu, Kai-Xian,Jensen, Paul,Try, Andrew C.
supporting information; experimental part
p. 4662 - 4670
(2010/10/19)

ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES
Disclosed is a compound of Formula (I) in which W and R1-R6 are defined herein. Also disclosed is a method of treating spinal muscular atrophy, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced directly or indirectly by mutation or frameshift.
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Page/Page column 47-48

(2009/05/29)

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Chemical Properties

Boiling Point: 112-114℃ (0.3 Torr)
Density: 1.216±0.06 g/cm3(Predicted)
PSA: 72.12000
LogP: 2.60310

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