- Preparation method and application of O-nitrobenzaldehyde
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The invention relates to a preparation method of o-nitrobenzaldehyde. The preparation method comprises the following steps: reacting o-nitrobenzyl triphenylphosphonium bromide with the required product o-nitrobenzaldehyde as raw materials to generate 1, 2-bis (o-nitrophenyl) ethylene, and oxidizing with ozone to obtain o-nitrobenzaldehyde. The preparation method has the beneficial effects that only a proper amount of alkali is used for catalysis in a condensation reaction, and an intermediate product 1, 2-bis (o-nitrophenyl) ethylene can be efficiently obtained by catalysis of an alkaline water reaction; and gas-liquid reaction is performed by using a micro-channel reactor to finally obtain the required nitrobenzaldehyde. The method has the advantages of less used raw materials, high reaction yield, less by-products and impurities, simple and feasible purification operation, and convenience for industrial production in workshops. Under the condition that the current chemical engineering environment protection and safety situation is severe, the process route can stably supply the important chemical intermediates of the type in an environment-friendly mode with the extremely high atom utilization rate.
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- Preparation method of O-nitrobenzaldehyde
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The invention relates to a preparation method of o-nitrobenzaldehyde, which comprises the following steps: preparing 1,2-bis(o-nitrophenyl)ethylene by using required products nitrobenzaldehyde and nitrotoluene as raw materials, and carrying out high-efficiency oxidation by using ozone with proper concentration to obtain the final product nitrobenzaldehyde. The preparation method has the beneficialeffects that only a proper amount of alkali is used for catalysis in the condensation reaction, and the intermediate product 1,2-bis(o-nitrophenyl)ethylene can be efficiently obtained by using a conventional solvent to carry out a reaction with water; a gas-liquid reaction then is carried out by using a micro-channel reactor to finally obtain the required nitrobenzaldehyde. The method has the advantages of low use amount of raw materials, high reaction yield, few byproducts and impurities, simple and feasible purification operation and convenience for industrial production in workshops.
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Paragraph 0033; 0042; 0043
(2020/02/14)
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