Synthesis of Novel Triazolyl/Oxadiazolyl/Thiadiazolyl-Piperazine as Potential Anticonvulsant Agents
Reaction of piperazine with chloroacetylchloride in dry acetone yield compound 1, which on reaction with hydrazine hydrate yielded compound 2, which was further reacted with various substituted phenylisothiocyanates in absolute alcohol to afford compounds
Synthesis of substituted piperazinyl semicarbazides and thiosemicarbazide: as possible acetyl cholinesterase (AChE) inhibitors
Some new N'-(N-aryl-N'-acetyl) piperazine-N4-aryl/alkyl semicarbazide and thiosemicarbazides have been synthesised as possible acetyl cholinesterase (AChE) inhibitors, by the condensation of N-aryl N'-piperazine acetic acid hydrazide with aryl or alkyl isocyanate and aryl isothiocyanates.
Sengupta,Agarwal,Mushtaq
p. 961 - 964
(2007/10/04)
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