- Synthesis, X-Ray Crystallography, Theoretical Investigation and Optical Properties of 2-Chloro-N-(2,4-dinitrophenyl) Acetamide
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Abstract: 2-Chloro-N-(2,4-dinitrophenyl) acetamide, 1, was synthesized and characterized by 1H and 13C NMR spectroscopy, ESI–MS, X-ray crystallography, and elemental analysis. This compound crystallizes in the monoclinic space group
- Jansukra, Piangkwan,Wattanathana, Worawat,Duangthongyou, Tanwawan,Wannapaiboon, Suttipong,Songsasean, Apisit,Suramitr, Songwut,Tuntulani, Thawatchai,Browning, C. Scott,Wannalerse, Boontana
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- Synthesis, Molecular Docking and Biological Evaluation of 2-Aryloxy-N-Phenylacetamide and N′-(2-Aryloxyoxyacetyl) Benzohydrazide Derivatives as Potential Antibacterial Agents
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A new class of 2-aryloxy-N-phenylacetamide and N′-(2-aryloxyoxyacetyl) benzohydrazide derivatives with different active moieties were synthesized and screened for their antibacterial activity. Structural characterization of synthesized compounds was perfo
- Yele, Vidyasrilekha,Azam, Mohammad Afzal,Wadhwani, Ashish D.
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- Synthesis and biological studies of N-phenyl substituted 2-(-5-(pyridine-4-yl)-1,3,4-oxadiazole-2-yl thio)acetamides
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As oxadiazole have proven to be good antimicrobial agents, Antitubercular, analgesic (peripheral and central) and antiinflammatory agents. A new series of oxadiazole derivatives were synthesized and characterized by 1H NMR, IR, GCMS sophisticated analytical instruments and were evaluated for their antimicrobial activity, antitubercular activity, toxicity as per standard guidelines, analgesic (peripheral and central) and antiinflammatory activity. Out of several derivatives synthesized a few of N-phenyl substituted 2-(5-(pyridine-4- yl)-1,3,4-oxadiazole-2-yl thio)acetamide explores good antimicrobial activity by using Cup-Plate method, antitubercular activity by middle brook 7H9 agar medium against H37Rv, analgesic activity by Writhing and Tail immersion method and antiinflammatory by rat paw edema method.
- Rao, M.E. Bhanoji,Rajurkar, Vikas G.
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experimental part
p. 2648 - 2652
(2012/01/05)
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- Baker's yeast-mediated regioselective reduction of 2,4-dinitroacylanilines: Synthesis of 2-substituted 6-nitrobenzimidazoles
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Several 2,4-dinitro-N-acylanilines were regioselectively reduced at the C-2 position by baker's yeast in slightly basic media (pH = 7.5) to afford 2-amino-4-nitroacylanilines, which were then cyclized under acidic conditions to the corresponding 2-substituted-6-nitrobenzimidazoles. The benzimidazoles thus obtained can be employed as precursors for bioactive derivatives.
- Olguín, Luís F.,Jiménez-Estrada, Manuel,Bárzana, Eduardo,Navarro-Oca?a, Arturo
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p. 340 - 342
(2007/10/03)
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- Activities of 2-carboxanilido 3-hydroxybenzo[b]thiophens against molluscs Biomphalaria
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The title compounds are shown to be nearly as active against molluscs as Niclosamide when they are either dihalogenated or monohalogenated and mononitrated on the benzene ring.
- Gayral,Buisson,Royer
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p. 187 - 189
(2007/10/02)
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