cas 6316-67-2, 3-Pyridinecarboxylicacid,4-methyl-,hydrazide(9CI) | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
6316-67-2

Articles about 6316-67-2Total 3 be found

Article title
Article abstract
Author
Journal number and time
Download

TRIAZOLE AGONISTS OF THE APJ RECEPTOR
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures where the definitions of the variables are provided herein.
-
Paragraph 0322; 0323

(2016/12/07)

Pyrido[4,3- e ][1,2,4]triazolo[4,3- a ]pyrazines as selective, brain penetrant phosphodiesterase 2 (PDE2) inhibitors
A novel series of pyrido[4,3-e][1,2,4]triazolo[4,3-a]pyrazines is reported as potent PDE2/PDE10 inhibitors with drug-like properties. Selectivity for PDE2 was obtained by introducing a linear, lipophilic moiety on the meta-position of the phenyl ring pending from the triazole. The SAR and protein flexibility were explored with free energy perturbation calculations. Rat pharmacokinetic data and in vivo receptor occupancy data are given for two representative compounds 6 and 12.
Rombouts, Frederik J. R.,Tresadern, Gary,Buijnsters, Peter,Langlois, Xavier,Tovar, Fulgencio,Steinbrecher, Thomas B.,Vanhoof, Greet,Somers, Marijke,Andrés, José-Ignacio,Trabanco, Andrés A.
supporting information
p. 282 - 286
(2015/03/30)

Inhibitors of VEGF receptors-1 and -2 based on the 2-((pyridin-4-yl)ethyl) pyridine template
We have developed a series of novel potent ((pyridin-4-yl)ethyl)pyridine derivatives active against kinases VEGFR-1 and -2. Both specific and dual ATP-competitive inhibitors of VEGFR-2 were identified. Kinase selectivity could be controlled by varying the
Kiselyov, Alexander S.,Semenova, Marina,Semenov, Victor V.,Milligan, Daniel
p. 1913 - 1919
(2007/10/03)

More Articles about upstream products of 6316-67-2

More Articles about downstream products of 6316-67-2

Chemical Properties

Melting Point: 176-177.3℃
Density: 1.195 g/cm³
Refractive Index: 1.573
PSA: 68.01000
LogP: 1.08470

Show more

Global suppliers and manufacturers of 6316-67-2total 9 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Dayang Chem (Hangzhou) Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 3.0-3.0 / Kilogram
Main Products:994
Country:

Henan Tianfu Chemical Co., Ltd.
Business Type:Lab/Research institutions
Min Order:1 Metric Ton
FOB Price:No Data
Main Products:67
Country:

Bluecrystal chem-union
Business Type:Trading Company
Min Order:1 Metric Ton
FOB Price:USD $ 1.0-1.0 / Metric Ton
Main Products:7
Country:

Antimex Chemical Limied
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:163
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

Chemlyte Solutions
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:198
Country:

ZHEJIANG JIUZHOU CHEM CO.,LTD
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:27
Country:

Finetech Industry Limited
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

CHEMSTEP
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 6316-67-2

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer