cas 63192-57-4, 3,3-DIHYDROXYBENZYL | Articles data

Articles about 63192-57-4Total 5 be found

Synthesis of hydroxy benzoin/benzil analogs and investigation of their antioxidant, antimicrobial, enzyme inhibition, and cytotoxic activities
In this study, hydroxy benzoin (1-7), benzil (8-14), and benzoin/benzil-O-β-D-glucosides (15-25) were synthesized to investigate their biological activities. An efficient method for synthesizing hydroxy benzoin compounds (1-7) was prepared from four diffe
Yayli, Nurettin,Kili?, G?zde,Celik, Gonca,Kahriman, Nuran,Kanbolat, Seyda,Bozdeveci, Arif,Karaoglu, Sengül Alpay,Aliyazicioglu, Rezzan,Sellitepe, Hasan Erdin?,Dogan, Inci Selin,Aydin, Ali
p. 788 - 804
(2021/07/26)

Design and synthesis of cyclic acylguanidines as BACE1 inhibitors
Based on the lead compound 1 reported in literature, a series of novel BACE1 inhibitors were designed and synthesized, among which compound 11 exhibited a 14-fold improvement in potency over the lead compound 1. This represents a good lead for the discovery of more promising BACE1 inhibitors for the potential treatment of AD.
Liu, Jia-Kuo,Gu, Wei,Cheng, Xiao-Rui,Cheng, Jun-Ping,Zhou, Wen-Xia,Nie, Ai-Hua
supporting information
p. 1327 - 1330
(2015/12/31)

2,2-dimethoxy-1,2-DI[4-(meth)acryloyloxy]phenylethane-1-one, method for producing the same, radical polymerization initiator and photocurable composition
The invention provides 2,2-dimethoxy-1,2-di-[4-(meth)acryloyloxy]phenylethane-1-one represented by the following formula (A): (wherein R1 and R2, which may be identical to or different from each other, each represent a hydrogen atom
-
Page/Page column 9-10; 13

(2015/07/07)

Hierarchical self-assembly of polycyclic heteroaromatic stars into snowflake patterns
Seeing stars: The two-dimensional patterns of the polycyclic heteroaromatic star molecules 1 on graphite vary with the side chain length. For n=12, frustrated self-assembly leads to hierarchically organized superstructures: up to 10?molecules form triangu
Jester, Stefan-S.,Sigmund, Eva,R?ck, Lisa M.,H?ger, Sigurd
supporting information; experimental part
p. 8555 - 8559
(2012/10/08)

Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors
A library of quinoxaline derivatives were prepared to target non-structural protein 1 of influenza A (NS1A) as a means to develop anti-influenza drug leads. An in vitro fluorescence polarization assay demonstrated that these compounds disrupted the dsRNA-NS1A interaction to varying extents. Changes of substituent at positions 2, 3 and 6 on the quinoxaline ring led to variance in responses. The most active compounds (35 and 44) had IC50 values in the range of low micromolar concentration without exhibiting significant dsRNA intercalation. Compound 44 was able to inhibit influenza A/Udorn/72 virus growth.
You, Lei,Cho, Eun Jeong,Leavitt, John,Ma, Li-Chung,Montelione, Gaetano T.,Anslyn, Eric V.,Krug, Robert M.,Ellington, Andrew,Robertus, Jon D.
supporting information; experimental part
p. 3007 - 3011
(2011/06/24)

Chemical Properties

Melting Point: 149-149.5 °C(Solv: water (7732-18-5); 1,2-dichloroethane (107-06-2))
Boiling Point: 500.4±35.0 °C(Predicted)
Density: 1.366±0.06 g/cm3(Predicted)
PKA: 8.42±0.10(Predicted)
PSA: 74.60000
LogP: 2.16340