- METHOD FOR THE PREPARATION OF (3S,3S') 4,4'-DISULFANEDIYLBIS (3-AMINOBUTANE 1-SULFONIC ACID)
-
The present invention relates to a new method for the preparation of (3S,3S') 4,4'-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
- -
-
Page/Page column 3; 10; 11
(2012/04/23)
-
- Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid)
-
The present invention relates to a new method for the preparation of (3S,3S') 4,4'-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
- -
-
Page/Page column 8
(2012/04/23)
-
- Synthesis and separation of tritiated inhibitors of aminopeptidase A and their prodrugs
-
With the aim of studying the bioavailability of two related aminopeptidase A (APA) inhibitors, we have synthesized tritiated disulfide prodrugs. These molecules, 4,4′-dithiobis-(3,3′-amino)-1,1′-butanesulfonic acid (RB 150) and its 2,2-dimethylpropyl este
- Inguimbert, Nicolas,Coric, Pascale,Dhotel, Helene,Llorens-Cortes, Catherine,Fournie-Zaluski, Marie-Claude,Roques, Bernard P.
-
p. 997 - 1005
(2007/10/03)
-