- Synthesizing method of indanone compound
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The invention discloses a synthesizing method of an indanone compound. The synthesizing method comprises the following steps of respectively adding a catalyst and an antioxidant into a reaction bottle, then adding a compound shown in a formula (2), adding a solvent, and reacting for 2 to 6h at the temperature of 70 to 120 DEG C under the argon protection atmosphere, so as to obtain the indanone compound, wherein the catalyst is selected from any one of Cu(OAc)2, CuCl2 (copper (II) chloride), CuBr2 (copper (II) bromide), CuO (copper oxide), CuF2 (copper fluoride), Cu(OTf) 2, Cu(OH)2 (copper hydroxide), Cu(NO3)2 (copper nitrate), CuCl (copper chloride), CuBr (copper bromide), CuI (cuprous iodide) and Cu2O (cuprous oxide); the oxidant is tert-butyl hydroperoxide; the solvent is toluene. The synthesizing method has the advantages that a novel concept of the indanone compound is provided; the copper catalyst is used, the price of copper is low, the reserve amount is rich, the environment-friendly effect is realized, and the hydroacylation reaction catalyzed by copper meets the requirements of green chemistry.
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Paragraph 0095; 0096; 0098-0101
(2018/11/04)
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- A bridge linking and its application of metal complexes
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The invention discloses a bridged metallocene complex, which is characterized by having a structural formula shown as the following A1, A2, A3 or A4. The invention also discloses a preparation method of ethylene propylene rubber. The ethylene propylene ru
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Paragraph 0074
(2017/02/23)
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- A method of preparation of ethylene-propylene-diene rubber
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The invention discloses a bridged metallocene complex, which is characterized by having a structural formula shown as the following A1, A2, A3 or A4. The invention also discloses a preparation method of ethylene propylene rubber. The ethylene propylene ru
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Paragraph 0048; 0072; 0076
(2017/03/23)
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- Rh-catalyzed reagent-free ring expansion of cyclobutenones and benzocyclobutenones
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Here we report a reagent-free rhodium-catalyzed ring-expansion reaction via C-C cleavage of cyclobutenones. A variety of poly-substituted cyclopentenones and 1-indanones can be synthesized from simple cyclobutenones and benzocyclobutenones. The reaction condition is near pH neutral without additional oxidants or reductants. The potential for developing a dynamic kinetic asymmetric transformation of this reaction has also been demonstrated. Further study supports the proposed pathway involving Rh-insertion into the cyclobutenone C-C bond, followed by β-hydrogen elimination, olefin insertion and reductive elimination.
- Chen, Peng-Hao,Sieber, Joshua,Senanayake, Chris H.,Dong, Guangbin
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p. 5440 - 5445
(2015/09/28)
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- Synthesis and molecular structures of zirconium and hafnium complexes bearing dimethylsilandiyl-bis-2,4,6-trimethylindenyl and dimethylsilandiyl-bis- 2-methyl-4,6-diisopropylindenyl ligands
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Zirconium and hafnium ansa-complexes containing 2,4,6-trialkyl-substituted indenyl fragments were synthesized and unambiguously characterized. Mixtures of rac- and meso-Me2Si(2-Me-4,6-R2C9H 3-η5)2MCl2, where R = Me, i-Pr and M = Zr, Hf, were obtained by a treatment of MCl4 by dilithium salts of the respective bis(2,4,6-trialkylindenyl)dimethylsilanes in toluene. Alternatively, better yields of the same complexes can be obtained by the reaction between metal tetrachlorides and indenyl-tin derivatives gave the desired ansa-metallocenes. All rac- and meso-complexes of Zr and Hf were isolated in an analytically pure form, and six of these ansa-metallocenes were characterized by X-ray crystal structure analysis.
- Izmer, Vyacheslav V.,Sorokin, Denis A.,Kuz'Mina, Lyudmila G.,Churakov, Andrei V.,Howard, Judith A.K.,Voskoboynikov, Alexander Z.
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p. 1067 - 1079
(2007/10/03)
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- Meldrum's acids as acylating agents in the catalytic intramolecular Friedel-Crafts reaction
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(Chemical Equation Presented) The intramolecular Friedel-Crafts acylation of aromatics with Meldrum's acid derivatives catalyzed by metal trifluoromethanesulfonates is reported. Meldrum's acids are easily prepared, functionalized, handled, and purified. The synthesis of polysubstituted 1-indanones from benzyl Meldrum's acids was investigated thoroughly, and it was shown that a variety of catalysts were effective, while accommodating a diversity of functional groups under mild conditions. The scope, limitations, and functional group tolerance (terminal alkene and alkyne, ketal, dialkyl ether, dialkyl thioether, aryl methyl ether, aryl TIPS and TBDPS ethers, nitrile- and nitro-substituted aryls, alkyl and aryl halides) for a variety of 5-benzyl (enolizable Meldrum's acids) and 5-benzyl-5-substituted Meldrum's acids (quaternized Meldrum's acids), forming 1-indanones and 2-substituted-1- indanones, respectively, are delineated. This method was further applied to the synthesis of 1-tetralones, 1-benzosuberones, and the potent acetylcholinesterase inhibitor donepezil. Rate of cyclization as a function of ring size was established for various benzocyclic ketones via competition experiments: 1-tetralones form faster than both 1-indanones and 1-benzosuberones, and 1-benzosuberones cyclize faster than 1-indanones.
- Fillion, Eric,Fishlock, Dan,Wilsily, Ashraf,Goll, Julie M.
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p. 1316 - 1327
(2007/10/03)
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- Process for preparing 1-indanones
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The present invention relates to a process for preparing 1-indanones of formula I: and isomers thereof, wherein R1, R2, R3, R4, R5, and R6 independently represent H or a C1-C20 hydrocarbon group or R1 and R2 or R2 and R3 or R3 and R4 and/or R5 and R6 together with the carbon atoms to which they are attached form a saturated or unsaturated 5- or 6-membered ring, said hydrocarbon group and/or said ring optionally containing one or more hetero atoms, said ring optionally being substituted with a C1-C4 hydrocarbon group, said process comprising reacting a compound of formula II: wherein R1, R2, R3, R4, R5, and R6 have the same meaning as defined above, with a chlorinating agent, followed by reaction with a Friedel-Crafts catalyst. The invention further relates to the preparation of the corresponding indenes.
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- Process for the preparation of substituted indenes and their use as ligand systems for metallocene catalysts
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The invention relates to a process for the preparation of a compound of the formula IV or IVa STR1 in which R1 -R5 are preferably hydrogen or alkyl, which comprises reacting a compound I STR2 with a compound II STR3 in which X1 and X2 are preferably halogen, to give the corresponding indanones, which are converted into the compounds IV and IVa by reduction and dehydration. The compounds IV and IVa are important intermediate products for the preparation of chiral metallocene complexes which are suitable catalyst components for olefin polymerization.
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- Process for the preparation of amorphous polymers of propylene
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It is possible to prepare substantially amorphous polymers of propylene endowed with high molecular weights, operating at temperatures of industrial interest, by carrying out the polymerization reaction of propylene in the presence of metallocene catalysts comprising particular bis-indenyl or bis-4,5,6,7-tetrahydroindenyl compounds substituted in the 2-position on the indenyl or tetrahydroindenyl groups.
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- Process for the preparation of substituted indanones, and their use
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1-Indanones of the formula IV or IVa STR1 in which R1 and R7 are preferably hydrogen or alkyl, or adjacent radicals R1 to R4 form a ring, are obtained in a one-step reaction by reacting a compound I STR2 with a compound of the formula II or a compound III STR3 in liquid hydrogen fluoride.
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- Process for the preparation of a high molecular weight olefin polymer
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A very active catalyst system for olefin polymerization comprises a cocatalyst, preferably an aluminoxane, and a metallocene of the formula I STR1 in which, preferably, M1 is Zr or Hf, R1 and R2 are alkyl or halogen, R3 is hydrogen, R4 to R6 and alkyl or aryl, --(CR8 R9)m --R7 --(CR8 R9)n is a single- or multi-membered chain, in which R' can also be a (substituted) hetero atom, and m+n is zero or 1.
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- Carbon-13 Nuclear Magnetic Resonance Spectra of Pterosin-Sesquiterpenes and Related Indan-1-one Derivatives
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Methyl derivatives of indan-1-one were prepared as models to aid in interpreting the carbon-13 nuclear magnetic resonance ((13)C-NMR) spectra of pterosin-sesquiterpenes which were isolated from bracken fern, Pteridium aquilinum var. latiusculum.The chemical shifts of the carbons of the methylindan-1-ones were assigned by the proton decoupling technique.All the (13)C-NMR signals of the pterosin-sesquiterpenes were assigned by means of selective proton decouplings, and from the (13)C-(1)H long-range couplings and (13)C chemical shifts of the model compounds.Keywords - indan-1-one derivative; methylindan-1-one; pterosin-sesquiterpene; methylindan-1-one synthesis; (1)H-NMR; (13)C-NMR; selective decoupling; C-H decoupling
- Fukuoka, Masamichi,Yoshihira, Kunitoshi,Natori, Shinsaku,Mihashi, Kunihide,Nishi, Masatoshi
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p. 3113 - 3128
(2007/10/02)
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